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Improving SIRT1 by trehalose supplementation reduces oxidative stress, inflammation, and histopathological scores in the kidney of aged rats.
Bahri F, Khaksari M, Movahedinia S, Shafiei B, Rajizadeh MA, Nazari-Robati M. Bahri F, et al. J Food Biochem. 2021 Oct;45(10):e13931. doi: 10.1111/jfbc.13931. Epub 2021 Sep 8. J Food Biochem. 2021. PMID: 34494279
In this study, we investigated the effects of trehalose on renal SIRT1 and kidney function in senescent rats. Trehalose (2% w/v) was administrated in drinking water for 1 month to male aged rats (24 months). ...
In this study, we investigated the effects of trehalose on renal SIRT1 and kidney function in senescent rats. Trehalose (2% w/v) was …
The administration of oral mucosal mesenchymal-derived stem cells improves hepatic inflammation, oxidative stress, and histopathology following traumatic brain injury.
Alizadeh E, Sabet N, Soltani Z, Khaksari M, Jafari E, Karamouzian S. Alizadeh E, et al. Transpl Immunol. 2023 Dec;81:101950. doi: 10.1016/j.trim.2023.101950. Epub 2023 Nov 2. Transpl Immunol. 2023. PMID: 37918577
OMSCs were obtained from oral mucosa biopsies. OMSCs were administered and administered i.v. at 1 and 24 h after TBI. Within 48 h after TBI, multiple parameters were analyzed, including inflammation, oxidative stress, and histopathological changes. ...Administration of OMS …
OMSCs were obtained from oral mucosa biopsies. OMSCs were administered and administered i.v. at 1 and 24 h after TBI. Within 48 h aft …
Transient brain hypothermia reduces the reperfusion injury of delayed tissue plasminogen activator and extends its therapeutic time window in a focal embolic stroke model.
Zarisfi M, Allahtavakoli F, Hassanipour M, Khaksari M, Rezazadeh H, Allahtavakoli M, Taghavi MM. Zarisfi M, et al. Brain Res Bull. 2017 Sep;134:85-90. doi: 10.1016/j.brainresbull.2017.07.007. Epub 2017 Jul 11. Brain Res Bull. 2017. PMID: 28710023
Male animals were subjected to embolic stroke and then randomly classified into control (saline), tPA (1mg/kg; i.v.), local hypothermia (LH), and tPA+LH. The drug was injected at 6 h after ischemia. ...
Male animals were subjected to embolic stroke and then randomly classified into control (saline), tPA (1mg/kg; i.v.), local hypotherm …
The effect of female sexual hormones on the intestinal and serum cytokine response after traumatic brain injury: different roles for estrogen receptor subtypes.
Khaksari M, Keshavarzi Z, Gholamhoseinian A, Bibak B. Khaksari M, et al. Can J Physiol Pharmacol. 2013 Sep;91(9):700-7. doi: 10.1139/cjpp-2012-0359. Epub 2013 Feb 21. Can J Physiol Pharmacol. 2013. PMID: 23984641
Adult female rats were ovariectomized and distributed among the following 9 groups: (i) sham trauma, (ii) TBI (Marmarou's method), (iii) vehicle (dimethylsulfoxide) treated, (iv) estrogen (E2) treated, (v) progesterone (P) treated, (vi) treated with E2+P, (vii) propylpyraz …
Adult female rats were ovariectomized and distributed among the following 9 groups: (i) sham trauma, (ii) TBI (Marmarou's method), (iii) veh …